This is a widely used method for preparing amino acids in the laboratory. Ethanamide amidate is reacted with the halogenated malonium ester , obtaining the compound which is alkylated and hydrolyzed to give a diacid , which decarboxylates to form the amino acid .
Amino Acid Synthesis - Malonica
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- Germán Fernández
- AMINO ACIDS AND PEPTIDES THEORY
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